5,6-Dihydrouridine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

5,6-Dihydrouridine 是在细菌，真核生物和一些古细菌中的 tRNA 的 D-环中的保守位置中发现的修饰碱基。

5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea.

5,6-Dihydrouridine (Dihydrouridine) is one of the posttranscriptionally modified nucleosides. It is a product of the reduction of uridine (U), and can be further modified to 5-methyldihydrouridine (m5D). 5,6-Dihydrouridine is commonly present in the tRNA from Bacteria, Eukaryota, and some Archaea. It is identified in six positions in the “D-loop” of the tRNA (16, 17, 20a, 20b) and in position 47 in the variable loop.

——

——

Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

——

——

5627-05-4

246.22

C9H14N2O6

>98% (HPLC)

In Vitro:?H2O 中的溶解度 : 100 mg/mL (406.14 mM; 超声助溶) DMSO 中的溶解度 : 35.71 mg/mL (145.03 mM; 超声助溶 )

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(=O)NC1=O

——

(-20℃)

With Ice Pack

≥ 2 years