SM-6586 ( —— )

产品货号. M33501 CAS No. 103898-38-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

SM-6586
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

SM-6586 是一种 calcium channel 的拮抗剂，同时能够抑制 Na+/H+ 和 Na+/Ca2+ exchange transport，主要用于研究脑血管疾病和高血压等疾病。
产品描述

SM-6586 is a calcium channel antagonist and inhibitor of Na+/H+ and Na+/Ca2+ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.
体外实验

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体内实验

In SM-6586-treated spontaneously hypertensive rats, the survival rate after bilateral common carotid artery ligation is higher, the brain water content is lower, and the ATP level is higher and lactate level. In focal ischemia models, the SM-treated group shows a reduction of T1 relaxation time. The brain water content is significantly decreased in the SM-treated group.
同义词

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通路

Membrane Transporter/Ion Channel
靶点

Sodium Channel
受体

Sodium Channel | Na+/Ca2+ Exchanger
研究领域

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适应症

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CAS Number

103898-38-0
分子量

489.52
分子式

C26H27N5O5
纯度

>98% (HPLC)
溶解度

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SMILES

O=C(C1=C(C)NC(C)=C(C1C2=CC([N+]([O-])=O)=CC=C2)C3=NC(CN(CC4=CC=CC=C4)C)=NO3)OC
化学全称

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