021-51111890
购物车（）
sales@molnova.cn
Neuropathiazol
CAS No. 880090-88-0
Neuropathiazol ( —— )
产品货号. M33442 CAS No. 880090-88-0
Neuropathiazol 是一种神经元分化诱导物，能选择性地诱导多能海马神经祖细胞神经元分化。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1036 | 有现货 |
|
| 10MG | ￥1549 | 有现货 |
|
| 25MG | ￥3032 | 有现货 |
|
| 50MG | ￥4399 | 有现货 |
|
| 100MG | ￥5922 | 有现货 |
|
| 200MG | ￥8001 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥775 | 有现货 |
|
生物学信息
-
产品名称Neuropathiazol
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Neuropathiazol 是一种神经元分化诱导物，能选择性地诱导多能海马神经祖细胞神经元分化。
-
产品描述Neuropathiazol, a neuronal differentiation inducer, selectively induces neuronal differentiation of multipotent hippocampal neural progenitor cells.
-
体外实验Neuropathiazol (5-15 μM; 5 hours) significantly slows cell proliferation without visible cytotoxic effects.Neuropathiazol (10 μM; 1-4 days) down-regulates Sox2 (a neural progenitor marker) and up-regulates NeuroD1 (a neuronal cell marker). Neuropathiazol also inhibits astroglial differentiation that is induced by LIF and BMP2.Neuropathiazol induces neuronal differentiation of multipotent adult hippocampal neural progenitor cells.Neuropathiazol can competitively suppress astrogliogenesis by LIF/BMP2/FBS in a dose-dependent manner.Cell Proliferation Assay Cell Line:HCN cells Concentration:5 μM, 10 μM, 15 μM Incubation Time:5 hours Result:Inhibited proliferation of HCN neural progenitor cells.RT-PCR Cell Line:HCN cells Concentration:10 μM Incubation Time:1 day, 4 days Result:Downregulated Sox2 and upregulated NeuroD1.
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number880090-88-0
-
分子量338.42
-
分子式C19H18N2O2S
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO 中的溶解度 : 33.33 mg/mL (98.49 mM; 超声助溶 )
-
SMILESCCOC(=O)C1=CC=C(C=C1)N(C)C1=CSC(=N1)C1=CC=CC=C1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Warashina M, et al. A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. Angew Chem Int Ed Engl. 2006 Jan 16;45(4):591-3.?
产品手册
关联产品
-
2'-DEOXYCYTIDINE-5'-...
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI 氧化有助于稳定期分枝杆菌中的抗生素致死率。
-
Prolactin Releasing ...
Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin. Human and rat Prolactin Releasing Peptide (1-31) binds to GPR10 with Kis of 1.03 and 0.33 nM, respectively.Prolactin-releasing peptide is a specific prolactin releasing peptide.
-
Ranatensin
Ranatensin 是一种十一肽和一种蛙皮素受体 (Bombesin Receptor) 激动剂，可从青蛙 (Rana pipiens) 等两栖动物的皮肤中分离得到。Ranatensin 可维持动物血压的动态平衡，与血管紧张素 (Bradykinin)、缓激肽 (Bradykinin) 或去甲肾上腺素 (Norepinephrine) 无交叉过敏反应。
