Bifluranol
CAS No. 34633-34-6
Bifluranol ( —— )
产品货号. M33302 CAS No. 34633-34-6
Bifluranol (BX341) 具有抗雄激素活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥2157 | 有现货 |
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| 10MG | ¥3088 | 有现货 |
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| 25MG | ¥4548 | 有现货 |
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| 50MG | ¥6026 | 有现货 |
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| 100MG | ¥7992 | 有现货 |
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| 200MG | ¥10530 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Bifluranol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Bifluranol (BX341) 具有抗雄激素活性。
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产品描述Bifluranol (BX341) is an anti-androgen.
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体外实验——
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体内实验The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog; Bifluranol is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [3H]Bifluranol to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat, 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL-1 (rat) or 1 ng Bifluranol equivalents mL-1 (ferret).
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同义词——
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通路Endocrinology/Hormones
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靶点Androgen Receptor (AR)
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受体Androgen Receptor
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研究领域——
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适应症——
化学信息
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CAS Number34633-34-6
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分子量292.32
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分子式C17H18F2O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (342.09 mM; 超声助溶 )
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SMILESCC[C@H]([C@H](C)c1ccc(O)c(F)c1)c1ccc(O)c(F)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Pope DJ, et al. Bifluranol, a novel fluorinated bibenzyl anti-androgen, its chemistry and disposition in different animal species. J Pharm Pharmacol. 1981 May;33(5):297-301.?
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