Bidisomide ( —— )

产品货号. M33120 CAS No. 116078-65-0

Bidisomide (SC40230) 是一种 I 类抗心律失常剂。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥2708	有现货
10MG	￥3772	有现货
25MG	￥5506	有现货
50MG	￥7589	有现货
100MG	￥9810	有现货
500MG	￥19890	有现货
1G	获取报价	有现货
1 mL x 10 mM in DMSO	￥3059	有现货

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生物学信息

产品名称

Bidisomide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Bidisomide (SC40230) 是一种 I 类抗心律失常剂。
产品描述

Bidisomide (SC40230) is a class I antiarrhythmic agent.
体外实验

——
体内实验

The antiarrhythmic effects of Bidisomide, a new class I antiarrhythmic drug is investigated in early-phase ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. In rats with ventricular arrhythmias induced by coronary artery reperfusion following a 5 min coronary occlusion, the antiarrhythmic effects of 5 mg/kg of Bidisomide are similar to those of the same doses of MXT and DSP. All three drugs significantly slow the heart rate.
同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

——
适应症

——

化学信息

CAS Number

116078-65-0
分子量

407.98
分子式

C22H34ClN3O2
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO 中的溶解度 : 250 mg/mL (612.78 mM; 超声助溶 )
SMILES

CC(C)N(CCC(CCN1CCCCC1)(C(N)=O)c1ccccc1Cl)C(C)=O
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Komori S, et al. Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide. Heart Vessels. 1995;1?

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