021-51111890
购物车（）
sales@molnova.cn
Bidisomide
CAS No. 116078-65-0
Bidisomide ( —— )
产品货号. M33120 CAS No. 116078-65-0
Bidisomide (SC40230) 是一种 I 类抗心律失常剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2708 | 有现货 |
|
| 10MG | ￥3772 | 有现货 |
|
| 25MG | ￥5506 | 有现货 |
|
| 50MG | ￥7589 | 有现货 |
|
| 100MG | ￥9810 | 有现货 |
|
| 500MG | ￥19890 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥3059 | 有现货 |
|
生物学信息
-
产品名称Bidisomide
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Bidisomide (SC40230) 是一种 I 类抗心律失常剂。
-
产品描述Bidisomide (SC40230) is a class I antiarrhythmic agent.
-
体外实验——
-
体内实验The antiarrhythmic effects of Bidisomide, a new class I antiarrhythmic drug is investigated in early-phase ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. In rats with ventricular arrhythmias induced by coronary artery reperfusion following a 5 min coronary occlusion, the antiarrhythmic effects of 5 mg/kg of Bidisomide are similar to those of the same doses of MXT and DSP. All three drugs significantly slow the heart rate.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number116078-65-0
-
分子量407.98
-
分子式C22H34ClN3O2
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO 中的溶解度 : 250 mg/mL (612.78 mM; 超声助溶 )
-
SMILESCC(C)N(CCC(CCN1CCCCC1)(C(N)=O)c1ccccc1Cl)C(C)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Komori S, et al. Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide. Heart Vessels. 1995;1?
产品手册
关联产品
-
Peimine
Peimine 是一种抑制剂，通过阻断 MAPK 和 NF-κB 信号通路来抑制 LPS 诱导的炎症细胞因子的产生。
-
Glycyrrhizin-6-dimet...
Glycyrrhizin-6′′-methylester (compound 22) 是一种甘草皂苷，能够从甘草根中分离得到。Glycyrrhizin-6′′-methylester 可作为糖苷配基参与葡萄糖醛酸甲酯的生成，产生甜味和甘草味，但没有苦味。这揭示了糖苷锥结合葡萄糖醛酸上的游离羧基对于天然甜味和甘草味觉的重要性。
-
4,5-dehydroisopsoral...
4'',5''-Dehydroisopsoralidin 是一种 β-葡萄糖醛酸酶 (β-glucuronidase) 抑制剂(IC50: 6.3 μM)。4'',5''-Dehydroisopsoralidin 具有抗炎和抗氧化作用。4'',5''-Dehydroisopsoralidin 可用于炎症和癌症的研究。
