Bidisomide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Bidisomide (SC40230) 是一种 I 类抗心律失常剂。

Bidisomide (SC40230) is a class I antiarrhythmic agent.

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The antiarrhythmic effects of Bidisomide, a new class I antiarrhythmic drug is investigated in early-phase ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. In rats with ventricular arrhythmias induced by coronary artery reperfusion following a 5 min coronary occlusion, the antiarrhythmic effects of 5 mg/kg of Bidisomide are similar to those of the same doses of MXT and DSP. All three drugs significantly slow the heart rate.

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Others

Other Targets

Others

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116078-65-0

407.98

C22H34ClN3O2

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 250 mg/mL (612.78 mM; 超声助溶 )

CC(C)N(CCC(CCN1CCCCC1)(C(N)=O)c1ccccc1Cl)C(C)=O

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(-20℃)

With Ice Pack

≥ 2 years