Enterolactone ( —— )

产品货号. M32134 CAS No. 78473-71-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Enterolactone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Enterolactone is a useful organic compound for research related to life sciences.
产品描述

Enterolactone is a useful organic compound for research related to life sciences.
体外实验

Enterolactone (25-75 μM; 48 hours) arrests the growth of MDA-MB-231 breast cancer cells in the ‘S’ phaseEnterolactone (25-75 μM; 15 hours) triggers apoptosis in MDA-MB-231 breast cancer cells via caspase-3 activation.Enterolactone inhibits TGF-β-induced migration of MDA-MB-231 breast cancer cells. Enterolactone inhibits TGF-β-induced invasion of MDA-MB-231 breast cancer cells through ECM. Enterolactone inhibits the TGF-β-induced EMT program in MDA-MB-231 breast cancer cells. Enterolactone reduces the formation of actin stress fibers by inhibiting the expression of CD44 and MAPK-p38. Enterolactone inhibits the ERK/NF-κB/Snail signaling pathway to revert TGF-β-induced EMT in MDA-MB-231 cells. Cell Viability Assay Cell Line:MDA-MB-231 cells Concentration:25, 50, 75 μM Incubation Time:48 hours Result:There was a non-significant increase (~24%) in the S phase population following treatment with 25 μM EL, whereas there were significant increases (~34% and ~39%) following treatment with 50 and 75 μM EL, respectively.
体内实验

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