2-Pyrrolidinone 是 γ-氨基丁酸 (GABA) 的内酰胺环化产物。氨己烯酸（VGB，一种抗癫痫药）会增加人脑中的γ-氨基丁酸（GABA）和相关代谢物，包括 2-吡咯烷酮。

SXC 2023 ((S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid) is a therapeutic prodrug of N-acetyl-L-cysteine for the treatment of CNS disorders and neurocognitive disorders, and can be used to treat glutamatergic dysfunction and psychiatric disorders in which oxidative stress plays a key role.

用作医药中间体。