1-Methyl-2-undecylquinolin-4(1H)-one ( —— )

产品货号. M31488 CAS No. 59443-02-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

1-Methyl-2-undecylquinolin-4(1H)-one
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth.
产品描述

1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression. It also shows moderate antiangiogenic activity against human tumor cells.
体外实验

1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity.
体内实验

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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计算器

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