Picrasidine Q

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.

Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.

Picrasidine Q (0~60 μM; 3 hours; ESCC cells) suppresses downstream signaling of FGFR2 in ESCC cells.Picrasidine Q (0~60 μM; 48 and 72 hours; ESCC cells) induces cell cycle arrest and apoptosis.Picrasidine Q (0~60 μM; 24~72 hours; ESCC cells) suppresses the growth of ESCC cells.Picrasidine Q (0~60 μM; 30 minutes; JB6Cl41 cells) inhibits proliferation by inhibition of G1/S cell cycle transition.Picrasidine Q (12.5, 25 or 50 μM) can inhibit the FGFR2 kinase activity in a dose-dependent manner. Western Blot Analysis Cell Line:ESCC cells Concentration:0~60 μM Incubation Time:3 hours Result:Suppressed downstream signaling of FGFR2 in ESCC cells.Apoptosis Analysis Cell Line:ESCC cells Concentration:0~60 μM Incubation Time:48 and 72 hours Result:Induced cell cycle arrest and apoptosis.Cell Cytotoxicity Assay Cell Line:ESCC cells Concentration:0~60 μM Incubation Time:24~72 hours Result:Suppressed the growth of ESCC cells.Cell Cycle Analysis Cell Line:JB6Cl41 cells Concentration:0~60 μM Incubation Time:30 minutes Result:Inhibited proliferation by inhibition of G1/S cell cycle transition.

——

——

Others

Other Targets

——

——

——

101219-61-8

266.3

C15H10N2O3

>98% (HPLC)

——

——

——

(-20℃)

With Ice Pack

≥ 2 years