1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolidine inhibits PAF-induced platelet aggregation with an IC50 value of 37.3 μM. value was 37.3 μM.

Cyanidin-3-glucoside

EG00229 是一种神经纤维蛋白 1 受体 (NRP1) 拮抗剂。EG00229 选择性抑制 VEGF-A 与 NRP1 b1 域的结合， IC50 为 3μM，但对 VEGFA 与 VEGFR-1 和 VEGFR-2 的结合没有影响。