021-51111890
购物车（）
sales@molnova.cn
Sar-[D-Phe8]-des-Arg9-Bradykinin
CAS No. 126959-88-4
Sar-[D-Phe8]-des-Arg9-Bradykinin ( —— )
产品货号. M30744 CAS No. 126959-88-4
Potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic activity in vivo.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Sar-[D-Phe8]-des-Arg9-Bradykinin
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic activity in vivo.
-
产品描述Potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic activity in vivo.
-
体外实验——
-
体内实验——
-
同义词——
-
通路GPCR/G Protein
-
靶点Bradykinin Receptor
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number126959-88-4
-
分子量975.11
-
分子式C47H66N12O11
-
纯度>98% (HPLC)
-
溶解度water:2 mg/mL
-
SMILES[H]N(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC1=CC=CC=C1)C(O)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Drapeau et al (1991) Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins. J.Pharmacol.Exp.Ther. 259 997 PMID:
产品手册
关联产品
-
Bradykinin (1-3)
Bradykinin (1-3) is a fragment of Bradykinin. Bradykinin is an activates pain receptors.
-
[Phe8Ψ(CH-NH)-Arg9]-...
Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin in vivo.
-
[Des-Arg9]-Bradykini...
[Des-Arg9]-Bradykinin 是一种缓激肽 (B1) 受体的激动剂，对 B1 受体表现出相对于 B2 受体的选择性。
