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Substance P (7-11)
CAS No. 51165-05-0
Substance P (7-11) ( —— )
产品货号. M30419 CAS No. 51165-05-0
Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥378 | 有现货 |
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| 5MG | ￥626 | 有现货 |
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| 10MG | ￥1093 | 有现货 |
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| 25MG | ￥1814 | 有现货 |
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| 50MG | ￥2716 | 有现货 |
|
| 100MG | ￥3807 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Substance P (7-11)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.
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产品描述Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.(In Vitro):Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM.
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体外实验Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number51165-05-0
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分子量612.78
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分子式C31H44N6O5S
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 1.96 mg/mL (3.20 mM)
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SMILES——
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化学全称Sequence:Phe-Phe-Gly-Leu-Met-NH2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Halliday DA, et al. The substance P fragment SP-(7-11) increases prostaglandin E2, intracellular Ca2+ and collagenase production in bovine articular chondrocytes. Biochem J. 1993 May 15;292 ( Pt 1):57-62.
产品手册
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