Substance P (7-11) ( —— )

产品货号. M30419 CAS No. 51165-05-0

Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
2MG	￥378	有现货
5MG	￥626	有现货
10MG	￥1093	有现货
25MG	￥1814	有现货
50MG	￥2716	有现货
100MG	￥3807	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

Substance P (7-11)
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.
产品描述

Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.(In Vitro):Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM.
体外实验

Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

——
研究领域

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适应症

——

化学信息

CAS Number

51165-05-0
分子量

612.78
分子式

C31H44N6O5S
纯度

>98% (HPLC)
溶解度

In Vitro:?H2O : 1.96 mg/mL (3.20 mM)
SMILES

——
化学全称

Sequence:Phe-Phe-Gly-Leu-Met-NH2

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

Halliday DA, et al. The substance P fragment SP-(7-11) increases prostaglandin E2, intracellular Ca2+ and collagenase production in bovine articular chondrocytes. Biochem J. 1993 May 15;292 ( Pt 1):57-62.

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