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ProTx II
CAS No. 484598-36-9
ProTx II ( —— )
产品货号. M30379 CAS No. 484598-36-9
Selective NaV1.7 channel blocker. Shifts activation gating positively and decreases current magnitude. Displays 100-fold selectivity over other sodium channel subtypes.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ProTx II
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Selective NaV1.7 channel blocker. Shifts activation gating positively and decreases current magnitude. Displays 100-fold selectivity over other sodium channel subtypes.
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产品描述Selective NaV1.7 channel blocker. Shifts activation gating positively and decreases current magnitude. Displays 100-fold selectivity over other sodium channel subtypes.
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体外实验——
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体内实验——
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同义词——
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通路Membrane Transporter/Ion Channel
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靶点Sodium Channel
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受体IC50: 0.3 nM (V1.7), 41 nM (v1.2), 102 nM (V1.3), 39 nM (V1.4), 79 nM (V1.5), 26 nM (V1.6), 146 nM (V1.8)
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研究领域——
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适应症——
化学信息
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CAS Number484598-36-9
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分子量3826.59
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分子式C168H250N46O41S8
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:{Tyr}{Cys}{Gln}{Lys}{Trp}{Met}{Trp}{Thr}{Cys}{Asp}{Ser}{Glu}{Arg}{Lys}{Cys}{Cys}{Glu}{Gly}{Met}{Val}(Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys25)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Trapencaine
Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.
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Lidocaine hydrochlor...
盐酸利多卡因盐是一种酰胺局部麻醉剂，在体外和体内具有抗炎特性。
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Silperisone HCl
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperisone HCl is used to treat recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, dystonia symptoms, cone tension syndrome, multiple sclerosis myospasm and myelitis. silperisone is a sodium channel protein type 2 alpha channel blocker. silperisone is an organosilicon similar to tolperisone, an organosilicon compound with centrally acting muscle relaxant properties.
