β-Amyloid 35-42
CAS No. 183292-41-3
β-Amyloid 35-42 ( —— )
产品货号. M30285 CAS No. 183292-41-3
β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称β-Amyloid 35-42
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.
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产品描述β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.
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体外实验β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure.The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing.Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments.
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体内实验——
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同义词——
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通路Membrane Transporter/Ion Channel
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靶点Beta Amyloid
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number183292-41-3
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分子量744.94
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分子式C33H60N8O9S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (67.12 mM)
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SMILES——
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化学全称Sequence:{Met}{Val}{Gly}{Gly}{Val}{Val}{Ile}{Ala}
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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MAO-B-IN-9
MAO-B-IN-9 (compound 16) 是一种有效的、选择性的、透过血脑屏障的、不可逆的、时间依赖性的 MAO-B (单胺氧化酶 B) 抑制剂,其 IC50 值为 0.18 μM。MAO-B-IN-9 可防止 Aβ1-42 诱导的神经元细胞死亡。MAO-B-IN-9 具有神经保护作用,其机制可能与 Aβ1-42 抗聚集作用有关。MAO-B-IN-9 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
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Amyloid β-Protein 10...
Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains the HHQK domain (residues 13-16) responsible for binding to microglial cells.
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β-Amyloid 1-9
This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism.
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