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Difopein TFA (396834-58-5 free base)
CAS No. ——
Difopein TFA (396834-58-5 free base) ( —— )
产品货号. M30250 CAS No. ——
Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Difopein TFA (396834-58-5 free base)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells.
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产品描述Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体14-3-3 protein
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量6501.19
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分子式C275H425N76F3O91S6
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:{Ser}{Ala}{Asp}{Gly}{Ala}{Pro}{His}{Cys}{Val}{Pro}{Arg}{Asp}{Leu}{Ser}{Trp}{Leu}{Asp}{Leu}{Glu}{Ala}{Asn}{Met}{Cys}{Leu}{Pro}{Gly}{Ala}{Ala}{Gly}{Leu}{Asp}{Ser}{Ala}{Asp}{Gly}{Ala}{Pro}{His}{Cys}{Val}{Pro}{Arg}{Asp}{Leu}{Ser}{Trp}{Leu}{Asp}{Leu}{Glu}{Ala}{Asn}{Met}{Cys}{Leu}{Pro}{Gly}{Ala}{Ala}{Gly}{Leu}{Glu}
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Masters SC, et al. 14-3-3 proteins mediate an essential anti-apoptotic signal. J Biol Chem. 2001 Nov 30;276(48):45193-200. Epub 2001 Sep 27.
产品手册
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