021-51111890
购物车（）
sales@molnova.cn
CTTHWGFTLC, CYCLIC
CAS No. 244082-19-7
CTTHWGFTLC, CYCLIC ( —— )
产品货号. M30200 CAS No. 244082-19-7
This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称CTTHWGFTLC, CYCLIC
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
-
产品描述This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
-
体外实验CTTHWGFTLC, CYCLIC inhibits endothelial and tumor cell migration in vitro.
-
体内实验CTTHWGFTLC, CYCLIC inhibits tumor progression in vivo, in mouse models.
-
同义词——
-
通路Metabolic Enzyme/Protease
-
靶点MMP
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number244082-19-7
-
分子量1166.33
-
分子式C52H71N13O14S2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称Sequence:{Cys}{Thr}{Thr}{His}{Trp}{Gly}{Phe}{Thr}{Leu}{Cys} (Disulfide Bridge: Cys1-Cys10)
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
Medina OP, et al. Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro. Cancer Res. 2001 May 15;61(10):3978-85.
产品手册
关联产品
-
Prinomastat
Prinomastat (AG3340) 是一种有效的选择性 MMP 抑制剂，具有 pM 亲和力，可抑制明胶酶（MMP-2 和 -9，Ki=50-150 pM）。
-
Bovine Type II Colla...
Collagens 是细胞外基质蛋白，在食品、化妆品、制药和生物医学行业有广泛的应用。Collagens 在皮肤、软骨、骨骼和结缔组织的结构和功能中起着重要作用。
-
Phloracetophenone
2', 4', 6'-TriHydroxyacetophenone 具有抗肥胖和降血脂作用，可能部分是通过抑制胰腺脂肪酶活性来延迟肠道对膳食脂肪的吸收来介导的。
