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CTTHWGFTLC, CYCLIC

CAS No. 244082-19-7

CTTHWGFTLC, CYCLIC ( —— )

产品货号. M30200 CAS No. 244082-19-7

This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    CTTHWGFTLC, CYCLIC
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
  • 产品描述
    This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
  • 体外实验
    CTTHWGFTLC, CYCLIC inhibits endothelial and tumor cell migration in vitro.
  • 体内实验
    CTTHWGFTLC, CYCLIC inhibits tumor progression in vivo, in mouse models.
  • 同义词
    ——
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    MMP
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    244082-19-7
  • 分子量
    1166.33
  • 分子式
    C52H71N13O14S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    Sequence:{Cys}{Thr}{Thr}{His}{Trp}{Gly}{Phe}{Thr}{Leu}{Cys} (Disulfide Bridge: Cys1-Cys10)

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Medina OP, et al. Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro. Cancer Res. 2001 May 15;61(10):3978-85.
产品手册
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