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Urotensin II (114-124), human TFA
CAS No. ——
Urotensin II (114-124), human TFA ( —— )
产品货号. M30114 CAS No. ——
Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Urotensin II (114-124), human TFA
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
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产品描述Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14.(In Vitro):Human Urotensin II (U-II) binds to recombinant human GPR14 with high affinity, and the binding is functionally coupled to calcium mobilization. Human Urotensin II induces concentration-dependent increases in intracellular calcium in a HEK-293 cell line expressing human GPR14 (EC50=0:62±0.17 nM, n=6).(In Vivo):Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体GPR14
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量1502.59
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分子式C66H86F3N13O20S2
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge: Cys5-Cys7)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Ames RS, et al. Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature. 1999 Sep 16;401(6750):282-6.
产品手册
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