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Adrenomedullin (AM) (22-52), human
CAS No. 159899-65-7
Adrenomedullin (AM) (22-52), human ( 22-52-Adrenomedullin (human) )
产品货号. M29956 CAS No. 159899-65-7
Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7581 | 有现货 |
|
| 10MG | ￥11495 | 有现货 |
|
| 25MG | ￥18321 | 有现货 |
|
| 50MG | ￥29388 | 有现货 |
|
| 100MG | ￥43110 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Adrenomedullin (AM) (22-52), human
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.
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产品描述Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.(In Vitro):Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist. Adrenomedullin (AM) (22-52), human competitively inhibits the binding of the Adrenomedullin in a dose-dependent manner, inhibits Adrenomedullin -induced cAMP accumulation in rat vascular smooth muscle cells.
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体外实验Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist.Adrenomedullin (AM) (22-52), human competitively inhibits the binding of the Adrenomedullin in a dose-dependent manner, inhibits Adrenomedullin -induced cAMP accumulation in rat vascular smooth muscle cells.
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体内实验——
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同义词22-52-Adrenomedullin (human)
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通路Others
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靶点Other Targets
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受体Adrenomedullin receptor, CGRP receptor
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研究领域——
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适应症——
化学信息
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CAS Number159899-65-7
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分子量3576.04
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分子式C159H252N46O48
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (27.96 mM)
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SMILES——
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化学全称Sequence:Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Champion HC, et al. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am J Physiol. 1997 Jan;272(1 Pt 2):R234-42.
产品手册
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