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Epieriocalyxin A
CAS No. 191545-24-1
Epieriocalyxin A ( —— )
产品货号. M29299 CAS No. 191545-24-1
Epieriocalyxin A 可以抑制 Caco-2 结肠癌细胞的生长。它可能是未来治疗结肠癌的潜在化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Epieriocalyxin A
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Epieriocalyxin A 可以抑制 Caco-2 结肠癌细胞的生长。它可能是未来治疗结肠癌的潜在化合物。
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产品描述Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.(In Vitro):Epieriocalyxin A (EpiA), a diterpenoid isolated from I. eriocalyx, suppressed Caco-2 colon cancer cell growth. EpiA induced annexin V flipping in the cell membrane and DNA fragment. We also showed that EpiA induced the generation of ROS in cells, as well as damage of the mitochondrial membrane. Western blot results showed that both JNK and ERK1/2 activation was decreased after EpiA treatment in a dose-dependent manner. EpiA increased the expression of caspase 3 and Bax and decreased Bcl2 expression.
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体外实验——
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体内实验——
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同义词——
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通路Apoptosis
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靶点PERK
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受体ERK
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研究领域——
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适应症——
化学信息
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CAS Number191545-24-1
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分子量344.4
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分子式C20H24O5
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C[C@@H]1C(C)(C)C=CC([C@](CO2)1[C@@](CC[C@@](C3)([H])[C@@H](C)C4=O)([H])[C@]43C2=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
