Lusianthridin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Lusianthridin 是来自 Dendrobium venustum 的天然产物。 Lusianthridin 在无毒浓度下表现出抗迁移特性。

Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.(In Vitro):Lusianthridin showed appreciable cytotoxicity against human lung cancer cell lines with IC50 values of 65.0 μg/mL. Lusianthridin (0-100 μM) inhibited cell viability at concentrations greater than 50 μM in both H460 and H292 cells. Lusianthridin significantly reduced the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentrations of 5, 10, and 20 μM, respectively.

Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells.Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively. Cell Viability Assay Cell Line:The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells.0-100 μM.Concentration:0-100 μM.Incubation Time:24 h.Result:Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells.

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Others

Other Targets

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87530-30-1

242.274

C15H14O3

>98% (HPLC)

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COc1cc(O)c-2c(CCc3cc(O)ccc-23)c1

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(-20℃)

With Ice Pack

≥ 2 years