Lirinidine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

(+)-Lirinidine具有抗氧化活性，能显着抑制黑色素瘤细胞的增殖；它还显示出对黑色素生成的有效抑制。

(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, arachidonic acid and platelet-activating factor-induced platelet aggregation.(In Vitro):Sixteen compounds were extracted and purified from the leaves of Liriodendron tulipifera. These compounds include aporphines, oxoaporphine, coumarin, sesquiterpene lactone, benzenoids, cyclitol and steroids. (+)-Norstephalagine (2) (an aporphine) and scopoletin (8) (a coumarin) were isolated from Liriodendron tulipifera leaves from the first time. The identified compounds were screened for their antiradical scavenging, metal chelating and ferric reducing power activities. The results have showed that these compounds have antioxidative activity. The study has also examined the chemopreventive property of the isolated compounds against human melanoma cells A375. The results showed that (-)-anonaine (1), (-)-liridinine (3), (+)-Lirinidine (6), lysicamine (7) and epitulipinolide diepoxide (9) significantly inhibited the proliferation of melanoma cells.

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Others

Other Targets

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54383-28-7

281.355

C18H19NO2

>98% (HPLC)

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COc1cc2CCN(C)[C@H]3Cc4ccccc4-c(c1O)c23

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(-20℃)

With Ice Pack

≥ 2 years