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Benzquinamide hydrochloride

CAS No. 113-69-9

Benzquinamide hydrochloride ( 3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride )

产品货号. M28949 CAS No. 113-69-9

BenzquinamideHClide 是一种止吐剂,由于外周血管阻力增加而增加动脉内压。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1245 有现货
10MG ¥1862 有现货
25MG ¥2995 有现货
50MG ¥4213 有现货
100MG ¥5328 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥1397 有现货

生物学信息

  • 产品名称
    Benzquinamide hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    BenzquinamideHClide 是一种止吐剂,由于外周血管阻力增加而增加动脉内压。
  • 产品描述
    Benzquinamide hydrochloride is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance.(In Vivo):Benzquinamide (0.5 to 5 mg/kg; i.v.) caused tachycardia, elevated blood norepinephrine levels, frequent ventricular arrhythmias, and brief hypotension. Ganglionic blockade by hexamethonium prior to administration of benzquinamide prevented the tachycardia and alterations in norepinephrine levels but prolonged the period of hypotension. In isolated mesenteric arterial preparations, benzquinamide interfered with the contractile force generated by potassium chloride, norepinephrine, and prostaglandin F2 alpha.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    TLR7
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    113-69-9
  • 分子量
    442.977
  • 分子式
    C22H35ClN2O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cl.CCN(CC)C(=O)C1CN2CCC3=CC(OC)=C(OC)C=C3C2CC1OC(C)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Nakamura T, et al. Synthesis and evaluation of 8-oxoadenine derivatives as potent Toll-like receptor 7 agonists with high water solubility. Bioorg Med Chem Lett. 2013 Feb 1;23(3):669-72.
产品手册
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