Benzquinamide hydrochloride
CAS No. 113-69-9
Benzquinamide hydrochloride ( 3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride )
产品货号. M28949 CAS No. 113-69-9
BenzquinamideHClide 是一种止吐剂,由于外周血管阻力增加而增加动脉内压。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥1245 | 有现货 |
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| 10MG | ¥1862 | 有现货 |
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| 25MG | ¥2995 | 有现货 |
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| 50MG | ¥4213 | 有现货 |
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| 100MG | ¥5328 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥1397 | 有现货 |
|
生物学信息
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产品名称Benzquinamide hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述BenzquinamideHClide 是一种止吐剂,由于外周血管阻力增加而增加动脉内压。
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产品描述Benzquinamide hydrochloride is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance.(In Vivo):Benzquinamide (0.5 to 5 mg/kg; i.v.) caused tachycardia, elevated blood norepinephrine levels, frequent ventricular arrhythmias, and brief hypotension. Ganglionic blockade by hexamethonium prior to administration of benzquinamide prevented the tachycardia and alterations in norepinephrine levels but prolonged the period of hypotension. In isolated mesenteric arterial preparations, benzquinamide interfered with the contractile force generated by potassium chloride, norepinephrine, and prostaglandin F2 alpha.
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体外实验——
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体内实验——
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同义词3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride
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通路Others
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靶点Other Targets
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受体TLR7
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研究领域——
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适应症——
化学信息
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CAS Number113-69-9
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分子量442.977
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分子式C22H35ClN2O5
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纯度>98% (HPLC)
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溶解度——
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SMILESCl.CCN(CC)C(=O)C1CN2CCC3=CC(OC)=C(OC)C=C3C2CC1OC(C)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Nakamura T, et al. Synthesis and evaluation of 8-oxoadenine derivatives as potent Toll-like receptor 7 agonists with high water solubility. Bioorg Med Chem Lett. 2013 Feb 1;23(3):669-72.
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