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GPI-1485
CAS No. 186268-78-0
GPI-1485 ( GM1485 )
产品货号. M28922 CAS No. 186268-78-0
GPI-1485 (GM1485) 是一种非免疫抑制性免疫亲和素配体，可促进中风后神经功能的改善和神经再生。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1254 | 有现货 |
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| 10MG | ￥1891 | 有现货 |
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| 25MG | ￥3060 | 有现货 |
|
| 50MG | ￥4455 | 有现货 |
|
| 100MG | ￥6012 | 有现货 |
|
| 200MG | ￥7947 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1454 | 有现货 |
|
生物学信息
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产品名称GPI-1485
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GPI-1485 (GM1485) 是一种非免疫抑制性免疫亲和素配体，可促进中风后神经功能的改善和神经再生。
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产品描述GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.(In Vitro):GPI-1485 induced cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF) .(In Vivo):GPI-1485 (5 mg/kg; intraperitoneal injection; 6-week period of daily) improved long-term neurological recovery in rats
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体外实验GPI-1485 (GM1485; 100 μM) induces cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF). Cell Viability Assay Cell Line:Normal human dermal fibroblasts (NHDF)Concentration:100 μM Incubation Time:Result:Induced cellular reprogramming and neural cell induction.
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体内实验GPI-1485 (GM1485; 5 mg/kg; intraperitoneal injection; 6-week period of daily) improves long-term neurological recovery in rats. Animal Model:Adult male Wistar rats, weighing 250-300 g Dosage:5 mg/kg Administration:Intraperitoneal injection; daily; for a total of 42 days Result:Administration improved neurological function and is consistent with an upregulation of endogenous neurogenesis following stroke in rats.
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同义词GM1485
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通路Others
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靶点Other Targets
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受体USP8
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研究领域——
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适应症——
化学信息
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CAS Number186268-78-0
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分子量241.287
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分子式C12H19NO4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (414.46 mM)
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SMILESCCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A.
产品手册
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