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6,6'-Dithiodinicotinic Acid
CAS No. 15658-35-2
6,6'-Dithiodinicotinic Acid ( —— )
产品货号. M28914 CAS No. 15658-35-2
6,6'-Dithiodinicotinic Acid 是一种非渗透性硫醇剂，会影响多种线粒体功能。在大鼠肝线粒体中，6,6'-Dithiodinicotinic Acid 仅抑制 Pi/OH- 载体； 6,6'-二硫代二烟酸和丙二酸正丁酯都是完全抑制 Pi 进入所必需的。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥273 | 有现货 |
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| 10MG | ￥392 | 有现货 |
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| 25MG | ￥641 | 有现货 |
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| 50MG | ￥917 | 有现货 |
|
| 100MG | ￥1242 | 有现货 |
|
| 200MG | ￥1782 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥186 | 有现货 |
|
生物学信息
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产品名称6,6'-Dithiodinicotinic Acid
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述6,6'-Dithiodinicotinic Acid 是一种非渗透性硫醇剂，会影响多种线粒体功能。在大鼠肝线粒体中，6,6'-Dithiodinicotinic Acid 仅抑制 Pi/OH- 载体； 6,6'-二硫代二烟酸和丙二酸正丁酯都是完全抑制 Pi 进入所必需的。
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产品描述6,6'-Dithiodinicotinic Acid is a non permeant thiol agent which affects several mitochondrial functions. In rat liver mitochondria, 6,6'-Dithiodinicotinic Acid inhibits only the Pi/OH- carrier; both 6,6'-Dithiodinicotinic Acid and n-butylmalonate are necessary to inhibit completely Pi entry.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Ferroptosis
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研究领域——
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适应症——
化学信息
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CAS Number15658-35-2
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分子量308.33
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分子式C12H8N2O4S2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (405.41 mM)
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SMILESOC(=O)c1ccc(SSc2ccc(cn2)C(O)=O)nc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Chen X, et al. Inhibiting Ferroptosis through Disrupting the NCOA4-FTH1 Interaction: A New Mechanism of Action. ACS Cent Sci. 2021 Jun 23;7(6):980-989.
产品手册
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