Pomalidomide 4'-PEG2-azide? ( 4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione )

产品货号. M28652 CAS No. 2271036-45-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Pomalidomide 4'-PEG2-azide?
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Pomalidomide 4'-PEG2-azide 是一种合成的 E3 连接酶配体-接头缀合物，含有基于 Pomalidomide 的 cereblon 配体和接头。
产品描述

Pomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands, linked by a linker; one of them is a ligand for E3 ubiquitin ligase and the other is a ligand for the target protein.
体外实验

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体内实验

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同义词

4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1.Khare P, et al. Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells. AAPS J. 2021;24(1):8. Published 2021 Dec 6.

计算器

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