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DL-Pyroglutamic acid
CAS No. 149-87-1
DL-Pyroglutamic acid ( —— )
产品货号. M28638 CAS No. 149-87-1
DL-焦谷氨酸对乙型肝炎表面抗原有很强的灭活作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥111 | 有现货 |
|
生物学信息
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产品名称DL-Pyroglutamic acid
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述DL-焦谷氨酸对乙型肝炎表面抗原有很强的灭活作用。
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产品描述DL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen.?
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体外实验DL-Pyroglutamic acid results 50 and 100% inactivation of the antigen of 0.01-0.025% and 0.025-0.05%, respectively.DL-Pyroglutamic acid is a possible glutamate antagonist, blocks glutamate miniature-end-plate potential in locust muscle-Druce and Bradford.
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体内实验DL-Pyroglutamic acid (0.775 mM/L) completely abolishes the myoclonic jerks and EEG spikes in rats model of epileptic by cobalt implantation in the sensorimotor cerebral cortex.
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同义词——
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通路Others
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靶点Other Targets
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受体Pyroptosis|Caspase-1|IL-1β|inflammation
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研究领域——
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适应症——
化学信息
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CAS Number149-87-1
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分子量129.114
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分子式C5H7NO3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (774.53 mM)
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SMILESO=C(O)C(CC1)NC1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Rabuffetti, M., Sciorati, C., Tarozzo, G., et al. Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines. Journal of Neuroscience 20, 4398-4404 (2000).
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