MMP-12 Inhibitor ( MMP408 | MMP12 )

产品货号. M28533 CAS No. 1258003-93-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

MMP-12 Inhibitor
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

MMP-12 Inhibitor 是一种选择性 MMP-12 抑制剂，对人、小鼠、大鼠和绵羊 MMP-12 的 IC50 分别为 2、160、320 和 22.3 nM。
产品描述

MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.(In Vitro):MMP-12 Inhibitor shows weaker activity against human MMP-3, MMP-13, and MMP-14 with IC50s of 351, 120, and 1100 nM.(In Vivo):In mice, MMP-12 Inhibitor (5 mg/kg, p.o.) effectively alleviates rhMMP-12-induced pulmonary inflammatory response by more than 50%.
体外实验

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体内实验

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同义词

MMP408 | MMP12
通路

Metabolic Enzyme/Protease
靶点

MMP
受体

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研究领域

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适应症

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计算器

产品手册

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