Fmoc-Lys-OH hydrochloride
CAS No. 139262-23-0
Fmoc-Lys-OH hydrochloride ( —— )
产品货号. M28362 CAS No. 139262-23-0
Fmoc-Lys-OH 盐酸盐是一种基于烷基链的 PROTAC 连接剂。 Fmoc-Lys-OH 盐酸盐是一种不可裂解的 ADC 连接子,用于合成抗体药物偶联物 (ADC)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | ¥89 | 有现货 |
|
生物学信息
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产品名称Fmoc-Lys-OH hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Fmoc-Lys-OH 盐酸盐是一种基于烷基链的 PROTAC 连接剂。 Fmoc-Lys-OH 盐酸盐是一种不可裂解的 ADC 连接子,用于合成抗体药物偶联物 (ADC)。
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产品描述Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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体外实验ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体NHE1
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研究领域——
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适应症——
化学信息
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CAS Number139262-23-0
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分子量404.89
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分子式C21H25ClN2O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (308.73 mM)
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SMILESCl.NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Guzman-Perez A, et al. Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. Bioorg Med Chem Lett. 2001 Mar 26;11(6):803-7.
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