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Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS No. 2341840-99-9
Thalidomide 4'-ether-alkylC2-amine hydrochloride ( halidomide-linker 6 )
产品货号. M28270 CAS No. 2341840-99-9
Thalidomide 4'-ether-alkalC2-amine HydroHClide 是一种合成的 E3 连接酶配体-接头缀合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥294 | 有现货 |
|
| 10MG | ￥472 | 有现货 |
|
| 25MG | ￥926 | 有现货 |
|
| 50MG | ￥1479 | 有现货 |
|
| 100MG | ￥2097 | 有现货 |
|
| 200MG | ￥2952 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Thalidomide 4'-ether-alkylC2-amine hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Thalidomide 4'-ether-alkalC2-amine HydroHClide 是一种合成的 E3 连接酶配体-接头缀合物。
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产品描述Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthesized E3 ligase ligand-linker conjugate.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词halidomide-linker 6
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通路Others
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靶点Other Targets
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受体MMP-12
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研究领域——
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适应症——
化学信息
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CAS Number2341840-99-9
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分子量353.76
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分子式C15H16ClN3O5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (353.35 mM)
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SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCN)=O.[H]Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Wei Li, et al. A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408). Journal of Medicinal Chemistry 2009 52 (7), 1799-1802
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