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Thalidomide-NH-CH2-COOH
CAS No. 927670-97-1
Thalidomide-NH-CH2-COOH ( (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine | 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid )
产品货号. M28260 CAS No. 927670-97-1
Thalidomide-NH-CH2-COOH 是一种合成的 E3 连接酶配体-接头缀合物，含有基于 Thalidomide 的 cereblon 配体和接头。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥94 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥94 | 有现货 |
|
生物学信息
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产品名称Thalidomide-NH-CH2-COOH
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Thalidomide-NH-CH2-COOH 是一种合成的 E3 连接酶配体-接头缀合物，含有基于 Thalidomide 的 cereblon 配体和接头。
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产品描述Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验——
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体内实验——
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同义词(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine | 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid
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通路Others
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靶点Other Targets
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受体α7 nAChR
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研究领域——
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适应症——
化学信息
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CAS Number927670-97-1
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分子量331.28
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分子式C15H13N3O6
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (150.93 mM)
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SMILESOC(CNc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lagostena L, et al. The partial alpha7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus. Neuropharmacology. 2008 Mar;54(4):676-85.
产品手册
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