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Metallo β-lactamase ligand 1
CAS No. 1087784-71-1
Metallo β-lactamase ligand 1 ( —— )
产品货号. M28184 CAS No. 1087784-71-1
Metallo β-lactamaseligand 1 是一种 B 类 β-内酰胺酶抑制剂，具有抗菌活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥150 | 有现货 |
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| 10MG | ￥238 | 有现货 |
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| 25MG | ￥476 | 有现货 |
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| 50MG | ￥697 | 有现货 |
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| 100MG | ￥1008 | 有现货 |
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| 200MG | ￥1494 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥151 | 有现货 |
|
生物学信息
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产品名称Metallo β-lactamase ligand 1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Metallo β-lactamaseligand 1 是一种 B 类 β-内酰胺酶抑制剂，具有抗菌活性。
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产品描述Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.(In Vitro):The toxicity of Metallo β-lactamase ligand 1 is extremely low in HeLa cells.(In Vivo):Administration of Metallo β-lactamase ligand 1 significantly improves the survival rate in mice infected with an experimental strain (E. coli strain into which a plasmid encoding class B β-lactamase (IMP-1) is introduced).
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体外实验One effective measure against β-lactam antibacterial resistant bacteria is to use an inhibitor of β-lactamase, the enzyme responsible for its resistance mechanism, together with an appropriate β-lactam antibacterial agent. The toxicity of Metallo-beta-lactamase ligand 1 (Compound A) is extremely low in HeLa cells.
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体内实验After infecting mice with an experimental strain (E. coli strain into which a plasmid encoding class B β-lactamase (IMP-1) is introduced), Metallo-beta-lactamase ligand 1 (compound A; 100 mg/kg; intraperitoneal injection) is administered, and life and death are observed. Administration of Metallo-beta-lactamase ligand 1 (compound A) significantly improves the survival rate.
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同义词——
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通路GPCR/G Protein
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靶点Antibacterial
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受体IL-1β| IL-10
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研究领域——
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适应症——
化学信息
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CAS Number1087784-71-1
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分子量219.21
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分子式C7H9NO5S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (1140.41 mM)
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SMILESCc1oc(C)c(c1C(O)=O)S(N)(=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Badria FA, Ameen M, Akl MR. Evaluation of cytotoxic compounds from calligonum comosum L. growing in Egypt. Z Naturforsch C J Biosci. 2007 Sep-Oct;62(9-10):656-60.
产品手册
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