N-Acetyltyramine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

N-乙酰酪胺是从菌株 M3-10 的发酵液中提取的活性化合物，该菌株产生群体感应抑制剂 (QSI) 化合物。 N-Acetyltyramine 抑制紫色杆菌 ATCC 12472 violacein 的产生和毒力因子，例如由铜绿假单胞菌 PAO1 产生的pyoverdine 产生，以及集群和抽搐运动。

N-Acetyltyramine is the active compound extracted from a fermentation broth of strain M3-10 which produces quorum-sensing inhibitor (QSI) compound. N-Acetyltyramine inhibits Chromobacterium violaceum ATCC 12472 violacein production and virulence factors, such as pyoverdine production, as well as swarming and twitching motilities, produced by Pseudomonas aeruginosa PAO1.(In Vitro):N-Acetyltyramine enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells (IC50 = 0.13 μg/ml).

N-Acetyltyramine enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml for doxorubicin alone.

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GPCR/G Protein

Antibacterial

Wee1

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1202-66-0

179.219

C10H13NO2

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (557.97 mM)

CC(=O)NCCc1ccc(O)cc1

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(-20℃)

With Ice Pack

≥ 2 years