N-(3-Aminopropyl)cyclohexylamine
CAS No. 3312-60-5
N-(3-Aminopropyl)cyclohexylamine ( —— )
产品货号. M28059 CAS No. 3312-60-5
N-(3-氨基丙基)环己胺是一种环己胺衍生物,是亚精胺合酶的选择性和竞争性抑制剂。 N-(3-氨基丙基)环己胺可用于神经系统疾病的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ¥258 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称N-(3-Aminopropyl)cyclohexylamine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述N-(3-氨基丙基)环己胺是一种环己胺衍生物,是亚精胺合酶的选择性和竞争性抑制剂。 N-(3-氨基丙基)环己胺可用于神经系统疾病的研究。
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产品描述N-(3-Aminopropyl)cyclohexylamine, a cyclohexylamine derivative, acts as a selective and competitive inhibitor of spermidine synthase. N-(3-Aminopropyl)cyclohexylamine can be used for the research of neurological diseases.(In Vitro):N-(3-Aminopropyl)cyclohexylamine at concentrations up to 10(-6) M did not affect the neuronal survival, but significantly blocked the survival-promoting effect of spermine (10(-8) M) . APCHA also blocked the spermine-induced promotion of neurite regeneration following axotomy . In primary cultured brain neurons, APCHA works as a spermine antagonist rather than as a spermine synthesis inhibitor .
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体FPR1|FPR2
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研究领域——
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适应症——
化学信息
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CAS Number3312-60-5
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分子量156.273
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分子式C9H20N2
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 100 mg/mL (639.92 mM)
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SMILESNCCCNC1CCCCC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Asahina Y, et al. Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure [published online ahead of print, 2020 May 24]. J Med Chem. 2020;10.1021/acs.jmedchem.9b02101.
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