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Lactisole
CAS No. 150436-68-3
Lactisole ( 2-(4-Methoxyphenoxy)propanoic acid )
产品货号. M28055 CAS No. 150436-68-3
Lactisole 是葡萄糖敏感受体的抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 200MG | ￥123 | 有现货 |
|
| 500MG | ￥198 | 有现货 |
|
| 1G | ￥285 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥94 | 有现货 |
|
生物学信息
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产品名称Lactisole
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Lactisole 是葡萄糖敏感受体的抑制剂。
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产品描述Lactisole is an inhibitor of the glucose-sensing receptor.(In Vitro):In MIN6 cells, in a dose-dependent manner, lactisole inhibited insulin secretion induced by sweeteners, acesulfame-K, sucralose and glycyrrhizin. The IC50 was ～4 mmol/l. Lactisole attenuated the elevation of cytoplasmic Ca2+ concentration ([Ca2+]c) evoked by sucralose and acesulfame-K but did not affect the elevation of intracellular cAMP concentration ([cAMP]c) induced by these sweeteners. Lactisole also inhibited the action of glucose in MIN6 cells. Thus, lactisole significantly reduced elevations of intracellular [NADH] and intracellular [ATP] induced by glucose, and also inhibited glucose-induced insulin secretion.
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体外实验——
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体内实验——
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同义词2-(4-Methoxyphenoxy)propanoic acid
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通路Others
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靶点Other Targets
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受体Apoptosis|PKG
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研究领域——
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适应症——
化学信息
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CAS Number150436-68-3
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分子量218.184
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分子式C10H11NaO4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (572.92 mM)
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SMILES[Na+].COc1ccc(OC(C)C([O-])=O)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Singh T, et al. Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis. Photochem Photobiol. 2012 Sep-Oct;88(5):1141-8.
产品手册
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