hSMG-1 inhibitor 11e

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

hSMG-1 抑制剂 11e 是一种有效的选择性 hSMG-1 激酶抑制剂，其 IC50 比 mTOR（IC50 为 45 nM）、PI3Kα/γ（IC50 为 61 nM 和 92 nM）和 CDK1/CDK2（IC50）高 900 倍。 32 μM 和 7.1 μM）。

hSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of 900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kα/γ (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 μM and 7.1 μM).(In Vitro):hSMG-1 inhibitor 11e exhibits an IC50 of 900-fold selectivity over mTOR (IC50 = 45 nM), PI3Kα/γ (IC50 = 61 nM), PI3Kγ (IC50 = 92 nM), CDK1(IC50 = 32 μM) and CDK2 (IC50 = 7.1 μM).

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Others

Other Targets

COX-1|COX-2|Xanthine Oxidase

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1402452-10-1

517.6

C26H27N7O3S

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (96.60 mM)

N/A

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(-20℃)

With Ice Pack

≥ 2 years