PQ-10

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

PQ-10 是一种 PDE-10 抑制剂。 PQ-10 诱导大脑葡萄糖代谢模式，这可能是一种潜在的转化生物标志物。

PQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.(In Vivo):In mice, PQ-10 shows a region-specific increase in 2-DG uptake in the globus pallidus (equivalent to the outer part of the primate pallidus) and lateral habenula .

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PQ-10 shows region-specific increases in 2-DG uptake in the globus pallidus (equivalent to the external segment of the globus pallidus in primates) and the lateral habenula in mice. Animal Model:24 –28 g male C57BL/6 mice, PDE10A WT and KO mice.Dosage:0.16, 0.63, 2.5, and 10 mg/kg Administration:s.c.Result:Showed region-specific increases in 2-DG uptake in the globus pallidus (equivalent to the external segment of the globus pallidus in primates) and the lateral habenula in mice.

PQ 10 | PQ10 | A844337 | A-844337 | A 844337

Angiogenesis

PDE

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927691-21-2

403.442

C22H21N5O3

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (61.97 mM)

COc1cc2ncnc(N3CCC(C3)Oc3cnc4ccccc4n3)c2cc1OC

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(-20℃)

With Ice Pack

≥ 2 years