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TCS PrP Inhibitor 13
CAS No. 34320-83-7
TCS PrP Inhibitor 13 ( 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One )
产品货号. M27727 CAS No. 34320-83-7
TCS PrP Inhibitor 13 是一种抗朊病毒剂，可抑制蛋白酶抗性朊病毒蛋白 (PrP-res) 的积累。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥276 | 有现货 |
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| 10MG | ￥459 | 有现货 |
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| 25MG | ￥892 | 有现货 |
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| 50MG | ￥1283 | 有现货 |
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| 100MG | ￥1854 | 有现货 |
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| 200MG | ￥2493 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥311 | 有现货 |
|
生物学信息
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产品名称TCS PrP Inhibitor 13
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TCS PrP Inhibitor 13 是一种抗朊病毒剂，可抑制蛋白酶抗性朊病毒蛋白 (PrP-res) 的积累。
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产品描述TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.(In Vitro):In Schwannoma cells, administration of 0-500 μM TCS PrP Inhibitor 13 reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and increases expression of cleaved caspase-3 significantly. TCS PrP Inhibitor 13 also significantly reduces the number of proliferating, Ki67-positive cells and total cell number in Schwannoma cells.
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体外实验TCS PrP Inhibitor 13 (0~500 μM; Schwannoma cells) significantly reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and significantly increases expression of cleaved caspase-3. TCS PrP Inhibitor 13 (Schwannoma cells) significantly reduces the number of proliferating, Ki67-positive cells and total cell number.
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体内实验——
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同义词5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number34320-83-7
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分子量281.271
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分子式C15H11N3O3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (355.53 mM)
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SMILES[O-][N+](=O)c1ccc(cc1)C1=NN(C(=O)C1)c1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ensslin HK, Kovar KA, Maurer HH. Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay. J Chromatogr B Biomed Appl. 1996 Aug 30;683(2):189-97.
