RS 67333 hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

有效且高选择性的 5-HT4 部分激动剂。

potent and highly selective 5-HT4 partial agonist.(In Vitro):RS 67333 hydrochloride exhibits affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT .

RS 67333 hydrochloride does exhibit affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT.

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RS 67333 HCl | RS 67333 (hydrochloride)

Others

Other Targets

c-Fgr|Lyn|Hck|Apoptosis

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168986-60-5

389.36

C19H30Cl2N2O2

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (128.42 mM)

Cl.CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1

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(-20℃)

With Ice Pack

≥ 2 years