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3,5-Dinitrocatechol
CAS No. 7659-29-2
3,5-Dinitrocatechol ( OR-486 | 3,5-Dinitropyrocatechol )
产品货号. M27677 CAS No. 7659-29-2
OR-486 是儿茶酚-O-甲基-转移酶 (COMT) 的抑制剂，可用于制备钼 (VI)- 3,5-二硝基儿茶酚复合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥266 | 有现货 |
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| 10MG | ￥380 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称3,5-Dinitrocatechol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述OR-486 是儿茶酚-O-甲基-转移酶 (COMT) 的抑制剂，可用于制备钼 (VI)- 3,5-二硝基儿茶酚复合物。
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产品描述OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.(In Vitro):OR-486 is highly effective (IC50 = 12 nM) and selective in inhibiting COMT activity in vitro.(In Vivo):In mouse trachea (β1-AR dominant), significant suppression of ISO-induced relaxation was observed with the addition of OR-486. In GP trachea, in the presence of clorgiline plus OR-486, both normetadrenaline (NMA) and metadrenaline (MA) (10-4 M) significantly suppressed ISO-induced relaxation.
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体外实验——
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体内实验——
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同义词OR-486 | 3,5-Dinitropyrocatechol
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通路Metabolic Enzyme/Protease
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靶点Transferase
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number7659-29-2
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分子量200.106
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分子式C6H4N2O6
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纯度>98% (HPLC)
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溶解度——
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SMILESOc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Plachká K, et al. Development, validation and comparison of UHPSFC and UHPLC methods for the determination of agomelatine and its impurities. J Pharm Biomed Anal. 2016 Jun 5;125:376-84.
