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1-Deoxymannojirimycin hydrochloride
CAS No. 73465-43-7
1-Deoxymannojirimycin hydrochloride ( —— )
产品货号. M27591 CAS No. 73465-43-7
1-Deoxymannojirimycin salticide 是一种选择性 α1,2-甘露糖苷酶抑制剂 (IC50: 20 μM)。 1-Deoxymannojirimycin salticide 也能抑制 HIV-1 菌株，但抗病毒活性较差。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2024 | 有现货 |
|
| 10MG | ￥3031 | 有现货 |
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| 25MG | ￥4948 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称1-Deoxymannojirimycin hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述1-Deoxymannojirimycin salticide 是一种选择性 α1,2-甘露糖苷酶抑制剂 (IC50: 20 μM)。 1-Deoxymannojirimycin salticide 也能抑制 HIV-1 菌株，但抗病毒活性较差。
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产品描述1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.(In Vitro):Exposure of such mutant virus strains to 1-Deoxymannojirimycin results in an enhanced suppression of mutant virus-induced cytopathicity in CEM cell cultures.When combined with CBAs at concentrations that showed poor if any suppression of mutant virus replication as single drugs, a synergistic antiviral activity of 1-Deoxymannojirimycin was observed.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体PPARβ|PPARδ
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研究领域——
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适应症——
化学信息
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CAS Number73465-43-7
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分子量199.63
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分子式C6H14ClNO4
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 100 mg/mL (500.93 mM)
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SMILESCl.OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kaupang ?, et al. Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. Eur J Med Chem. 2015 Apr 13;94:229-36.
产品手册
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