Alloxazine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Alloxazine (Isoalloxazine) 是一种 A2 受体拮抗剂，其对 A2B 受体的选择性比对 A2A 受体的选择性高约 10 倍。

Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.

Alloxazine (0-30 μM, 20 min) inhibits cyclic AMP production in PGT-β cells. Cell Viability Assay Cell Line:PGT-β cells Concentration:0-30 μM Incubation Time:20 min Result:Inhibited the cyclic AMP generation concentration-dependently with an IC50 of 2.9 μM.

Alloxazine (1 μmol/L; cortical surface suffusion for 0-20 min) suppresses NECA-induced vasodilation. Animal Model:Male Sprague-Dawley rats Dosage:1 μmol/L Administration:Cortical surface suffusion; 1 μmol/L once Result:Significantly suppressed vasodilation with increased EC25 value of 0.60 μmol/L.

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Apoptosis

Adenosine Receptor

glucokinase

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490-59-5

214.184

C10H6N4O2

>98% (HPLC)

In Vitro:?DMSO : 5 mg/mL (23.34 mM)

O=c1[nH]c2nc3ccccc3nc2c(=O)[nH]1

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(-20℃)

With Ice Pack

≥ 2 years