CGP 35348

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化小鼠新生脑损伤后的神经肌肉协调和空间学习。

CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.(In Vivo):In male Wistar rats, CGP 35348(100, 300, and 900 mg/kg) produced an increase in the duration of non-REM sleep and rapid eye movement (REM) sleep and reduced strongly spike-wave discharges.

——

Animal Model:Eight male Wistar rats Dosage:100, 300, and 900 mg/kg?Administration:Intraperitoneally given Result:Produced an increase in the duration of REM sleep compared to the saline-injected control group at 100 and 300 mg/kg.

——

Others

Other Targets

——

——

——

123690-79-9

225.22

C8H20NO4P

>98% (HPLC)

In Vitro:?H2O : 83.33 mg/mL (369.99 mM)

CCOC(OCC)P(CCCN)(O)=O

——

(-20℃)

With Ice Pack

≥ 2 years