Ataciguat
CAS No. 254877-67-3
Ataciguat ( HMR-1766 )
产品货号. M27435 CAS No. 254877-67-3
Ataciguat (HMR-1766) 是一种有效且特异性的可溶性鸟苷酸环化酶 (sGC) 激活剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥708 | 有现货 |
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| 10MG | ¥1131 | 有现货 |
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| 25MG | ¥2213 | 有现货 |
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| 50MG | ¥3283 | 有现货 |
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| 100MG | ¥4437 | 有现货 |
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| 200MG | ¥6192 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥898 | 有现货 |
|
生物学信息
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产品名称Ataciguat
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Ataciguat (HMR-1766) 是一种有效且特异性的可溶性鸟苷酸环化酶 (sGC) 激活剂。
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产品描述Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.(In Vitro):Ataciguat induces the relaxation in aortic rings or coronary rings. In the presence of nitric oxide synthase (NOS) inhibitor, the endothelium effect was abolished to DETA-NO or ataciguat, in both vessels. Ataciguat was able to induce NO production in HUVECs cells. In the presence of NOS inhibitor, the NO production induced by ataciguat was abolished.
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体外实验——
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体内实验——
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同义词HMR-1766
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通路Others
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靶点Other Targets
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受体PGE|ATPase|Potassium Channel
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研究领域——
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适应症——
化学信息
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CAS Number254877-67-3
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分子量576.48
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分子式C21H19Cl2N3O6S3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (173.46 mM)
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SMILESClc1ccc(s1)S(=O)(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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trans-Petroselinic A...
Trans-Petroselinic acid, the trans isomer of petroselinic acid and an isomer of oleic acid, is detected in the milk fat of cows, goats, and ewes, as well as human breast milk. In HepG2 cells, when treated with trans-petroselinic acid (100 μM), there is an increase in the cellular content of triacylglycerols and cholesterol esters. Additionally, it upregulates the transcription of genes associated with fatty acid synthesis (SREBP-1c, ACACA, FASN, SCD1) and cholesterol synthesis (HMGCR, HMGCS1, FDFT1, SREBP-2).
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2-(4-Hydroxyphenylaz...
2-(4-Hydroxyphenylazo)benzoicacid is a spectrophotometric probe that shows changes in absorption spectra upon binding to proteins and binds to bovine serum proteins.
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Estredox
E2-CDS (Estradiol 17-Dihydrotrigonelline) 是一种基于氧化还原的雌二醇 (E2) 化学输送系统。E2-CDS 能够持续且大脑选择性地输送雌二醇。
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