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Ataciguat

CAS No. 254877-67-3

Ataciguat ( HMR-1766 )

产品货号. M27435 CAS No. 254877-67-3

Ataciguat (HMR-1766) 是一种有效且特异性的可溶性鸟苷酸环化酶 (sGC) 激活剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥708 有现货
10MG ¥1131 有现货
25MG ¥2213 有现货
50MG ¥3283 有现货
100MG ¥4437 有现货
200MG ¥6192 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥898 有现货

生物学信息

  • 产品名称
    Ataciguat
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Ataciguat (HMR-1766) 是一种有效且特异性的可溶性鸟苷酸环化酶 (sGC) 激活剂。
  • 产品描述
    Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.(In Vitro):Ataciguat induces the relaxation in aortic rings or coronary rings. In the presence of nitric oxide synthase (NOS) inhibitor, the endothelium effect was abolished to DETA-NO or ataciguat, in both vessels. Ataciguat was able to induce NO production in HUVECs cells. In the presence of NOS inhibitor, the NO production induced by ataciguat was abolished.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    HMR-1766
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    PGE|ATPase|Potassium Channel
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    254877-67-3
  • 分子量
    576.48
  • 分子式
    C21H19Cl2N3O6S3
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (173.46 mM)
  • SMILES
    Clc1ccc(s1)S(=O)(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kim DH, et al. Metabolism of liriodendrin and syringin by human intestinal bacteria and their relation to in vitro cytotoxicity. Arch Pharm Res. 1999 Feb;22(1):30-4.
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