This is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger a defensive reaction from the immune system. Before insertion of the foreign peptides into the binding groove, a place-holding peptide CLIP is removed. This is accomplished by the molecule DM, which is shown to increase the dissociation rate of a CLIP peptide from class II.

IMR-1是一类新型Notch抑制剂，针对转录激活，IC50为6 μMol/L。

m-PEG2-Br 是一种基于 PEG 的 PROTAC 连接子，可用于 PROTAC 的合成。