α-Guanidinoglutaric Acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

α-胍基戊二酸存在于猫大脑皮层钴诱导的致癫痫病灶组织中。

α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric Acid-induced seizures are associated with abnormal serotonergic function and that they are initiated by a decrease in the 5-HT level.(In Vivo):α-Guanidinoglutaric Acid induced epileptic seizures in rats after intraventricular administration. Sporadic low-voltage spikes appeared 4 min after the administration of α-Guanidinoglutaric Acid. Spikes increased in voltage 6 min after the administration. Multiple spikes appeared 10 min after the administration, and they reached maximal frequency 30 min after the administration. The epileptic discharges disappeared 100 min after the administration. The 5-HT level increased in the right and left cortices 3 min after the administration. The 5-HT level decreased in the mid-brain 5 min after the administration and subsequently in all regions of the brain 10 min after the administration. No change in the 5-HT level was found 30 min and 100 min after the administration.

——

——

——

Others

Other Targets

PTK

——

——

73477-53-9

189.17

C6H11N3O4

>98% (HPLC)

——

NN=CN[C@@H](CCC(O)=O)C(O)=O

——

(-20℃)

With Ice Pack

≥ 2 years