Anecortave Acetate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Anecortave acetate 是一种有效的眼部血管抑制剂。Anecortave acetate 抑制由许多不同的血管生成因子诱导的新血管形成，也能增加纤溶酶原激活物抑制子 1 (PAI-1) mRNA表达。Anecortave acetate 可用于研究眼部新生血管疾病。

Anecortave Acetate, an angiostatic steroid, is used for proteomics research.

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Anecortave acetate (5 μl of a 10% suspension; Injected into eyes) significantly inhibits pathologic retinal angiogenesis and increases PAI-1 mRNA levels. Animal Model:Sprague-Dawley albino rats (intravitreally injected with premixed antibiotics to influence retinal vessel growth) Dosage:5 μl of a 10% suspension of Anecortave acetate Administration:Injected into eyes Result:significantly inhibited pathologic retinal angiogenesis in this model, while not significantly affecting normal intraretinal vessels.Increased 6-to-9-fold PAI-1 mRNA at 1 to 3 days after injection.

Anecortave Acetate | Anecortave | Al 3789 | NSC 15475 | NSC 24345 | Retaane

Others

Other Targets

Ligand for E3 Ligase

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7753-60-8

386.488

C23H30O5

>98% (HPLC)

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CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3=CC[C@]12C

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(-20℃)

With Ice Pack

≥ 2 years