p-Cresyl sulfate potassium

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

对甲基苯基硫酸钾是一种原型蛋白质结合尿毒症毒素，源自酪氨酸和苯丙氨酸通过肝脏的代谢产物。

p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver.

Cell Viability Assay Cell Line:Primary osteoblastic cells Concentration:0.05, 0.125, 0.25, 0.5 mM Incubation Time:24 h Result:Decreased cell viability in a dose-dependent manner.Cell Proliferation Assay Cell Line:Primary osteoblastic cells Concentration:0.05, 0.125, 0.25, 0.5 mM Incubation Time:24 h Result:Increased DNA fragmentation and decreased cell proliferation.Western Blot Analysis Cell Line:Primary osteoblastic cells Concentration: 0.125 mM Incubation Time:24 h Result:Induced rapid and sustained phosphorylation of JNK.

Animal Model:CKD mice modrlDosage:10 mg/kg Administration:i.p.Result:Increased fasting plasma glucose concentration and plasma cholesterol levels.

Potassium p-tolyl sulfate | p-Tolyl sulfate potassium salt | p-Cresol sulfate potassium

Proteasome/Ubiquitin

Endogenous Metabolite

cholinesterase

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——

91978-69-7

226.29

C7H7KO4S

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (552.39 mM)

[K+].Cc1ccc(OS([O-])(=O)=O)cc1

——

(-20℃)

With Ice Pack

≥ 2 years