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Biotin-ONP
CAS No. 33755-53-2
Biotin-ONP ( (+)-Biotin 4-nitrophenyl ester )
产品货号. M27001 CAS No. 33755-53-2
(+)-Biotin-ONP 是一种基于烷基链的 PROTAC 连接体，可用于 PROTAC 的合成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ￥89 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Biotin-ONP
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述(+)-Biotin-ONP 是一种基于烷基链的 PROTAC 连接体，可用于 PROTAC 的合成。
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产品描述(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词(+)-Biotin 4-nitrophenyl ester
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通路Others
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靶点Other Targets
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受体HDAC1
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研究领域——
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适应症——
化学信息
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CAS Number33755-53-2
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分子量365.4
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分子式C16H19N3O5S
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纯度>98% (HPLC)
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溶解度——
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SMILES[H][C@]12CS[C@@H](CCCCC(=O)Oc3ccc(cc3)[N+]([O-])=O)[C@@]1([H])NC(=O)N2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Patnaik D, et al. Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration. ACS Chem Neurosci. 2021 Jan 20;12(2):271-284.
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