m-PEG12-OH ( Dodecaethylene Glycol Monomethyl Ether )

产品货号. M26969 CAS No. 2050595-03-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

m-PEG12-OH
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

m-PEG12-OH 是一种基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。
产品描述

m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
体外实验

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体内实验

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同义词

Dodecaethylene Glycol Monomethyl Ether
通路

Others
靶点

Other Targets
受体

DENV NS2B-NS3 protease
研究领域

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适应症

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1.Watowich, Stanley J, et al. SMALL-MOLECULE INHIBITORS OF DENGUE VIRUS PROTEASES. US20150141521A1.

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