mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.

22393-62-0_peak 2 exhibits some aspects of the antiestrogenic activity and other actions that may be connected to the estrogenic properties. A mixture of the (Z)- and (E)-isomers (Broparestrol, INN) is used in dermatology.

AVE5688 是糖原磷酸化酶 (glycogen phosphorylase (GP)) 抑制剂，抑制兔肌肉糖原磷酸化酶 rmGPb 和 rmGPa 的活性，IC50 值分别为 430 nM 和 915 nM，Kd 值分别为 170 nM 和 530 nM；AVE5688 可用于二型糖尿病的研究。